Visit the Archive

Bookmark this page on your mobile

QR Code image

What is this?

Toledo Legal News - News OSU study finds fecal transplant alleviates some autism symptoms

 

A new study led by Ohio State University researchers has found that a fecal transplant in autistic children with gastrointestinal distress eases some of the behavioral symptoms in addition to rebalancing the gut.

The study, which was published in the journal Microbiome, explored the link between behavioral symptoms of autism and gastrointestinal distress and found improvement in both conditions following a fecal transplant and subsequent treatment.

In the study of 18 children with autism and moderate to severe gastrointestinal problems, parents and doctors said they saw positive changes that lasted at least eight weeks after the treatment, a university press release detailed.

Children without autism were included for comparison of bacterial and viral gut composition prior to the study.

"Transplants are working for people with other gastrointestinal problems," said Ann Gregory, one of the study's lead authors and a microbiology graduate student at The Ohio State University. "And, with autism, gastrointestinal symptoms are often severe, so we thought this could be potentially valuable.

"Following treatment, we found a positive change in gastrointestinal symptoms and neurological symptoms overall."

Gregory, along with her adviser and co-author Matthew Sullivan, conducted the research while at the University of Arizona. Other lead researchers on the project are from Arizona State University and Northern Arizona University.

Previous research had established that children with autism typically have fewer types of some important bacteria in their guts and less bacterial diversity overall - a difference that held true in this study. The cause could be attributed to prescription of antibiotics in the first three years of life, researchers believe.

Gregory used genetic testing to examine the viral diversity in the guts of the treated children, which rebounded quickly, becoming more similar to the donor's microbiome.

"Those donor viruses seemed to help," she said.

In the study, the researchers used a method called microbiota transfer therapy, which started with the children receiving a two-week course of antibiotics to wipe out much of their existing gut flora, the press release explained.

Doctors next gave them an initial high-dose fecal transplant in liquid form.

In the seven to eight weeks that followed, the children drank smoothies blended with a lower-dose powder.

There currently exists no approved pharmaceutical treatment for autism.

The Arizona Board of Regents, the Autism Research Institute and the Gordon and Betty Moore Foundation offered support in the study.

KEITH ARNOLD, Daily Reporter Staff Writer

Attorney suspended for two years

The Ohio Supreme Court recently suspended a Barberton attorney from the practice of law for two years with the last six months stayed based on discrepancies in her handling of two criminal cases.

Date Published: February 24, 2017

Fund your 529 with tax refund

Your tax refund makes a great CollegeAdvantage 529 fund. It’s also a great and easy saving strategy. The average 2015 federal tax refund was $2,466. By adding $2,500 a year to a 529 plan, you could cover as much as 40% of college at an Ohio public university, based on 18 years at 6% growth.

Date Published: February 24, 2017

Toledo finishes up Earl Yestingsmeier Match Play win over DePaul

No. 5 seed Toledo tallied a 4-2 victory over No. 7 seed DePaul on Tuesday, February 14 in the final round of the Earl Yestingsmeier Match Play event. With the win, the Rockets finish 1-1-1 at the sixth-annual event. Mid-American Conference member Ball State served as the tournament's host at the Lake Jovita Golf Course (Par 72, 7,153 Yards).

Date Published: February 24, 2017

Trucking firm that violated unemployment comp laws loses appeal

A Fostoria-based trucking company lost its case in the 10th District Court of Appeals recently when a panel of three judges found that the company was properly found to have violated Ohio unemployment compensation laws.

Date Published: February 22, 2017

Apps help travelers keep up fitness routines

Creating and sticking to a fitness routine while traveling is difficult - trying to use the hotel gym, run on the beach or searching for a safe jogging route isn't always easy.

Date Published: February 21, 2017

Gov. Kasich sets new execution schedule in response to federal court order

Recently, Governor John R. Kasich issued a revised schedule for eight upcoming executions. This revised schedule is in response to the U.S. Court of Appeals for the Sixth Circuit’s pending review of a challenge to Ohio’s execution procedures brought by death row inmates. The Court is not expected to issue its ruling in the case before the next scheduled execution on February 15. The February 15 execution would be that of Ronald Phillips who was sentenced to death in 1993 for the rape and murder of his girlfriend’s three-year-old daughter, Sheila Marie Evans.